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## org.biojavax.bio.seq
Class ThinRichSequence

    java.lang.Object
      org.biojava.utils.AbstractChangeable
          org.biojavax.bio.SimpleBioEntry
              org.biojavax.bio.seq.ThinRichSequence

All Implemented Interfaces:
  Comparable, Annotatable, FeatureHolder, Sequence, SymbolList, Changeable, BioEntry, RichSequence, RankedCrossRefable, RichAnnotatable

Direct Known Subclasses:
  SimpleRichSequence

    public class ThinRichSequence

extends SimpleBioEntry
implements RichSequence

A simple implementation of RichSequence. It has no sequence data, and delegates to a RichSequenceHandler to do sequence handling.

Since:
  1.5
Author:
  Richard Holland

Nested Class Summary

Nested classes/interfaces inherited from interface org.biojavax.bio.seq.RichSequence
`RichSequence.IOTools, RichSequence.Terms, RichSequence.Tools`

Nested classes/interfaces inherited from interface org.biojava.bio.Annotatable
`Annotatable.AnnotationForwarder`

Nested classes/interfaces inherited from interface org.biojava.bio.seq.FeatureHolder
`FeatureHolder.EmptyFeatureHolder`

Field Summary

Fields inherited from interface org.biojavax.bio.seq.RichSequence
`CIRCULAR, SYMLISTVERSION`

Fields inherited from interface org.biojavax.bio.BioEntry
`COMMENT, DESCRIPTION, DIVISION, IDENTIFIER, RANKEDCROSSREF, RANKEDDOCREF, RELATIONS, SEQVERSION, TAXON`

Fields inherited from interface org.biojava.bio.Annotatable
`ANNOTATION`

Fields inherited from interface org.biojava.bio.symbol.SymbolList
`EDIT, EMPTY_LIST`

Fields inherited from interface org.biojava.bio.seq.FeatureHolder
`EMPTY_FEATURE_HOLDER, FEATURES, SCHEMA`

Constructor Summary
`protected` | `ThinRichSequence()`
`` | `ThinRichSequence(Namespace ns, String name, String accession, int version, Alphabet alpha, Double seqversion)` Creates a new instance of ThinRichSequence.

Method Summary
`boolean` | `containsFeature(Feature f)` Check if the feature is present in this holder.
`int` | `countFeatures()` Count how many features are contained.
`Feature` | `createFeature(Feature.Template ft)` Create a new Feature, and add it to this FeatureHolder.
`void` | `edit(Edit edit)` Apply an edit to the SymbolList as specified by the edit object.
`Iterator<Feature>` | `features()` Iterate over the features in no well defined order. Warning this method gives access to the original Collection not a copy.
`FeatureHolder` | `filter(FeatureFilter filter)` Query this set of features using a supplied `FeatureFilter`.
`FeatureHolder` | `filter(FeatureFilter fc, boolean recurse)` Return a new FeatureHolder that contains all of the children of this one that passed the filter fc.
`Alphabet` | `getAlphabet()` The alphabet that this SymbolList is over.
`protected String` | `getAlphabetName()`
`boolean` | `getCircular()` Is the sequence circular? Circularity has implications for work with locations and any coordinate work eg symbolAt(int i).
`Set<Feature>` | `getFeatureSet()` The features for this sequence. Warning this method gives access to the original Collection not a copy.
`SymbolList` | `getInternalSymbolList()` A special function that returns the SymbolList that this RichSequence is based around.
`FeatureFilter` | `getSchema()` Return a schema-filter for this `FeatureHolder`.
`protected int` | `getSequenceLength()`
`Double` | `getSeqVersion()` The version of the associated symbol list.
`String` | `getURN()` A Uniform Resource Identifier (URI) which identifies the sequence represented by this object.
`Iterator` | `iterator()` An Iterator over all Symbols in this SymbolList.
`int` | `length()` The number of symbols in this SymbolList.
`void` | `removeFeature(Feature f)` Remove a feature from this FeatureHolder.
`String` | `seqString()` Stringify this symbol list.
`protected void` | `setAlphabetName(String alphaname)`
`void` | `setCircular(boolean circular)` Circularises the `Sequence`.
`void` | `setFeatureSet(Set<Feature> features)` Sets the features of this sequence. Warning this method gives access to the original Collection not a copy.
`protected void` | `setSequenceLength(int length)`
`void` | `setSeqVersion(Double seqVersion)` Sets the version of the associated symbol list.
`SymbolList` | `subList(int start, int end)` Return a new SymbolList for the symbols start to end inclusive.
`String` | `subStr(int start, int end)` Return a region of this symbol list as a String.
`Symbol` | `symbolAt(int index)` Return the symbol at index, counting from 1.
`List` | `toList()` Returns a List of symbols.

Methods inherited from class org.biojavax.bio.SimpleBioEntry
`addComment, addRankedCrossRef, addRankedDocRef, addRelationship, compareTo, equals, getAccession, getAnnotation, getComments, getDescription, getDivision, getId, getIdentifier, getName, getNamespace, getNoteSet, getRankedCrossRefs, getRankedDocRefs, getRelationships, getRichAnnotation, getTaxon, getVersion, hashCode, removeComment, removeRankedCrossRef, removeRankedDocRef, removeRelationship, setDescription, setDivision, setId, setIdentifier, setNoteSet, setRankedCrossRefs, setTaxon, toString`

Methods inherited from class org.biojava.utils.AbstractChangeable
`addChangeListener, addChangeListener, generateChangeSupport, getChangeSupport, hasListeners, hasListeners, isUnchanging, removeChangeListener, removeChangeListener`

Methods inherited from class java.lang.Object
`clone, finalize, getClass, notify, notifyAll, wait, wait, wait`

Methods inherited from interface org.biojavax.bio.BioEntry
`addComment, addRankedDocRef, addRelationship, getAccession, getComments, getDescription, getDivision, getIdentifier, getName, getNamespace, getRankedDocRefs, getRelationships, getTaxon, getVersion, removeComment, removeRankedDocRef, removeRelationship, setDescription, setDivision, setIdentifier, setTaxon`

Methods inherited from interface org.biojavax.RichAnnotatable
`getNoteSet, getRichAnnotation, setNoteSet`

Methods inherited from interface org.biojava.bio.Annotatable
`getAnnotation`

Methods inherited from interface org.biojava.utils.Changeable
`addChangeListener, addChangeListener, isUnchanging, removeChangeListener, removeChangeListener`

Methods inherited from interface org.biojavax.RankedCrossRefable
`addRankedCrossRef, getRankedCrossRefs, removeRankedCrossRef, setRankedCrossRefs`

Methods inherited from interface java.lang.Comparable
`compareTo`

Methods inherited from interface org.biojava.bio.seq.Sequence
`getName`

Constructor Detail

### ThinRichSequence

    public ThinRichSequence(Namespace ns,
                            String name,
                            String accession,
                            int version,
                            Alphabet alpha,
                            Double seqversion)

  Creates a new instance of ThinRichSequence. Note the use of Double for seqversion, which indicates that it is nullable.

  Parameters:
    `ns` - the namespace for this sequence.
    `name` - the name of the sequence.
    `accession` - the accession of the sequence.
    `version` - the version of the sequence.
    `seqversion` - the version of the symbols for the sequence.

### ThinRichSequence

    protected ThinRichSequence()

Method Detail

### getSeqVersion

    public Double getSeqVersion()

  The version of the associated symbol list. Note the use of an object for the value means that it can be nulled.

  Specified by:
    `getSeqVersion` in interface `RichSequence`
  Returns:
    the version

### setSeqVersion

    public void setSeqVersion(Double seqVersion)
                       throws ChangeVetoException

  Sets the version of the associated symbol list. Note the use of an object for the value means that it can be nulled.

  Specified by:
    `setSeqVersion` in interface `RichSequence`
  Parameters:
    `seqVersion` - the version to set.
  Throws:
    `ChangeVetoException` - if it doesn't want to change.

### setCircular

    public void setCircular(boolean circular)
                     throws ChangeVetoException

  Circularises the `Sequence`. The circular length can then be said to be the length of the sequence itself.

  Specified by:
    `setCircular` in interface `RichSequence`
  Parameters:
    `circular` - set to true if you want it to be circular
  Throws:
    `ChangeVetoException` - if the change is blocked. Some implementations may choose not to support circularisation and should throw an exception here. Some implementations may only support this method for certain Alphabets.

### getCircular

    public boolean getCircular()

  Is the sequence circular? Circularity has implications for work with locations and any coordinate work eg symbolAt(int i). Classes that allow it should test this method when working with coordinates or locations / features.

  Specified by:
    `getCircular` in interface `RichSequence`
  Returns:
    true if the this is circular else false.

### edit

    public void edit(Edit edit)
              throws IndexOutOfBoundsException,
                     IllegalAlphabetException,
                     ChangeVetoException

  Apply an edit to the SymbolList as specified by the edit object.

  ## Description

  All edits can be broken down into a series of operations that change contiguous blocks of the sequence. This represent a one of those operations.

  When applied, this Edit will replace 'length' number of symbols starting a position 'pos' by the SymbolList 'replacement'. This allow to do insertions (length=0), deletions (replacement=SymbolList.EMPTY_LIST) and replacements (length>=1 and replacement.length()>=1).

  The pos and pos+length should always be valid positions on the SymbolList to:

  - be edited (between 0 and symL.length()+1).
  - To append to a sequence, pos=symL.length()+1, pos=0.
  - To insert something at the beginning of the sequence, set pos=1 and length=0.

  ## Examples

  `

       SymbolList seq = DNATools.createDNA("atcaaaaacgctagc");
       System.out.println(seq.seqString());

       // delete 5 bases from position 4
       Edit ed = new Edit(4, 5, SymbolList.EMPTY_LIST);
       seq.edit(ed);
       System.out.println(seq.seqString());

       // delete one base from the start
       ed = new Edit(1, 1, SymbolList.EMPTY_LIST);
       seq.edit(ed);

       // delete one base from the end
       ed = new Edit(seq.length(), 1, SymbolList.EMPTY_LIST);
       seq.edit(ed);
       System.out.println(seq.seqString());

       // overwrite 2 bases from position 3 with "tt"
       ed = new Edit(3, 2, DNATools.createDNA("tt"));
       seq.edit(ed);
       System.out.println(seq.seqString());

       // add 6 bases to the start
       ed = new Edit(1, 0, DNATools.createDNA("aattgg");
       seq.edit(ed);
       System.out.println(seq.seqString());

       // add 4 bases to the end
       ed = new Edit(seq.length() + 1, 0, DNATools.createDNA("tttt"));
       seq.edit(ed);
       System.out.println(seq.seqString());

       // full edit
       ed = new Edit(3, 2, DNATools.createDNA("aatagaa");
       seq.edit(ed);
       System.out.println(seq.seqString());

  `

  Specified by:
    `edit` in interface `SymbolList`
  Parameters:
    `edit` - the Edit to perform
  Throws:
    `IndexOutOfBoundsException` - if the edit does not lie within the SymbolList
    `IllegalAlphabetException` - if the SymbolList to insert has an incompatible alphabet
    `ChangeVetoException` - if either the SymboList does not support the edit, or if the change was vetoed

### symbolAt

    public Symbol symbolAt(int index)
                    throws IndexOutOfBoundsException

  Return the symbol at index, counting from 1.

  Specified by:
    `symbolAt` in interface `SymbolList`
  Parameters:
    `index` - the offset into this SymbolList
  Returns:
    the Symbol at that index
  Throws:
    `IndexOutOfBoundsException` - if index is less than 1, or greater than the length of the symbol list

### toList

    public List toList()

  Returns a List of symbols.

  This is an immutable list of symbols. Do not edit it.

  Specified by:
    `toList` in interface `SymbolList`
  Returns:
    a List of Symbols

### subStr

    public String subStr(int start,
                         int end)
                  throws IndexOutOfBoundsException

  Return a region of this symbol list as a String.

  This should use the same rules as seqString.

  Specified by:
    `subStr` in interface `SymbolList`
  Parameters:
    `start` - the first symbol to include
    `end` - the last symbol to include
  Returns:
    the string representation
  Throws:
    `IndexOutOfBoundsException` - if either start or end are not within the SymbolList

### subList

    public SymbolList subList(int start,
                              int end)
                       throws IndexOutOfBoundsException

  Return a new SymbolList for the symbols start to end inclusive.

  The resulting SymbolList will count from 1 to (end-start + 1) inclusive, and refer to the symbols start to end of the original sequence.

  Specified by:
    `subList` in interface `SymbolList`
  Parameters:
    `start` - the first symbol of the new SymbolList
    `end` - the last symbol (inclusive) of the new SymbolList
  Throws:
    `IndexOutOfBoundsException`

### seqString

    public String seqString()

  Stringify this symbol list.

  It is expected that this will use the symbol's token to render each symbol. It should be parsable back into a SymbolList using the default token parser for this alphabet.

  Specified by:
    `seqString` in interface `SymbolList`
  Returns:
    a string representation of the symbol list

### length

    public int length()

  The number of symbols in this SymbolList.

  Specified by:
    `length` in interface `SymbolList`
  Returns:
    the length

### iterator

    public Iterator iterator()

  An Iterator over all Symbols in this SymbolList.

  This is an ordered iterator over the Symbols. It cannot be used to edit the underlying symbols.

  Specified by:
    `iterator` in interface `SymbolList`
  Returns:
    an iterator

### getAlphabet

    public Alphabet getAlphabet()

  The alphabet that this SymbolList is over.

  Every symbol within this SymbolList is a member of this alphabet. `alphabet.contains(symbol) == true` for each symbol that is within this sequence.

  Specified by:
    `getAlphabet` in interface `SymbolList`
  Returns:
    the alphabet

### setAlphabetName

    protected void setAlphabetName(String alphaname)
                            throws IllegalSymbolException,
                                   BioException

  Throws:
    `IllegalSymbolException`
    `BioException`

### getAlphabetName

    protected String getAlphabetName()

### setSequenceLength

    protected void setSequenceLength(int length)

### getSequenceLength

    protected int getSequenceLength()

### getURN

    public String getURN()

  A Uniform Resource Identifier (URI) which identifies the sequence represented by this object. For sequences in well-known database, this may be a URN, e.g.

       urn:sequence/embl:AL121903

  It may also be a URL identifying a specific resource, either locally or over the network

       file:///home/thomas/myseq.fa|seq22
       http://www.mysequences.net/chr22.seq

  Specified by:
    `getURN` in interface `Sequence`
  Returns:
    the URI as a String

### filter

    public FeatureHolder filter(FeatureFilter fc,
                                boolean recurse)

  Return a new FeatureHolder that contains all of the children of this one that passed the filter fc. This method is scheduled for deprecation. Use the 1-arg filter instead.

  Specified by:
    `filter` in interface `FeatureHolder`
  Parameters:
    `fc` - the FeatureFilter to apply
    `recurse` - true if all features-of-features should be scanned, and a single flat collection of features returned, or false if just immediate children should be filtered.

### createFeature

    public Feature createFeature(Feature.Template ft)
                          throws BioException,
                                 ChangeVetoException

  Create a new Feature, and add it to this FeatureHolder. This method will generally only work on Sequences, and on some Features which have been attached to Sequences.

  Specified by:
    `createFeature` in interface `FeatureHolder`
  Throws:
    `BioException` - if something went wrong during creating the feature
    `ChangeVetoException` - if this FeatureHolder does not support creation of new features, or if the change was vetoed

### removeFeature

    public void removeFeature(Feature f)
                       throws ChangeVetoException,
                              BioException

  Remove a feature from this FeatureHolder.

  Specified by:
    `removeFeature` in interface `FeatureHolder`
  Throws:
    `ChangeVetoException` - if this FeatureHolder does not support feature removal or if the change was vetoed
    `BioException` - if there was an error removing the feature

### containsFeature

    public boolean containsFeature(Feature f)

  Check if the feature is present in this holder.

  Specified by:
    `containsFeature` in interface `FeatureHolder`
  Parameters:
    `f` - the Feature to check
  Returns:
    true if f is in this set

### filter

    public FeatureHolder filter(FeatureFilter filter)

  Query this set of features using a supplied `FeatureFilter`.

  Specified by:
    `filter` in interface `FeatureHolder`
  Parameters:
    `filter` - the `FeatureFilter` to apply.
  Returns:
    all features in this container which match `filter`.

### getFeatureSet

    public Set<Feature> getFeatureSet()

  The features for this sequence. Warning this method gives access to the original Collection not a copy. This is required by Hibernate. If you modify the object directly the behaviour may be unpredictable.

  Specified by:
    `getFeatureSet` in interface `RichSequence`
  Returns:
    a set of RichFeature objects.

### setFeatureSet

    public void setFeatureSet(Set<Feature> features)
                       throws ChangeVetoException

  Sets the features of this sequence. Note that it is not checked to see if the features actually belong to this sequence, you'd best check that yourself and make changes using feature.setParent() if necessary. Warning this method gives access to the original Collection not a copy. This is required by Hibernate. If you modify the object directly the behaviour may be unpredictable.

  Specified by:
    `setFeatureSet` in interface `RichSequence`
  Parameters:
    `features` - the features to assign to this sequence, replacing all others. Must be a set of RichFeature objects.
  Throws:
    `ChangeVetoException` - if they could not be assigned.

### getSchema

    public FeatureFilter getSchema()

  Return a schema-filter for this `FeatureHolder`. This is a filter which all `Feature`s immediately contained by this `FeatureHolder` will match. It need not directly match their child features, but it can (and should!) provide information about them using `FeatureFilter.OnlyChildren` filters. In cases where there is no feature hierarchy, this can be indicated by including `FeatureFilter.leaf` in the schema filter.

  For the truly non-informative case, it is possible to return `FeatureFilter.all`. However, it is almost always possible to provide slightly more information that this. For example, `Sequence` objects should, at a minimum, return `FeatureFilter.top_level`. `Feature` objects should, as a minimum, return `FeatureFilter.ByParent(new FeatureFilter.ByFeature(this))`.

  Specified by:
    `getSchema` in interface `FeatureHolder`
  Returns:
    the schema filter

### features

    public Iterator<Feature> features()

  Iterate over the features in no well defined order. Warning this method gives access to the original Collection not a copy. This is required by Hibernate. If you modify the object directly the behaviour may be unpredictable.

  Specified by:
    `features` in interface `FeatureHolder`
  Returns:
    an Iterator

### countFeatures

    public int countFeatures()

  Count how many features are contained.

  Specified by:
    `countFeatures` in interface `FeatureHolder`
  Returns:
    a positive integer or zero, equal to the number of features contained

### getInternalSymbolList

    public SymbolList getInternalSymbolList()

  A special function that returns the SymbolList that this RichSequence is based around. This should _not_ be the RichSequence object itself, as this function is used to perform actions on the symbol list without referring to the RichSequence object directly.

  Specified by:
    `getInternalSymbolList` in interface `RichSequence`
  Returns:
    the internal SymbolList of the RichSequence, NOT the RichSequence object itself.

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