If you are upgrading from a WBIA release prior to 2.2.0, you need to define a new response queue, as follows. If you already have release 2.2.0 or later, you do not need to perform this task.
WebSphere Business Integration Adapters version 2.2.0 requires an additional WebSphere MQ queue, a response queue. Define this queue using a method listed under Ways to define queues. In Updates to the connector configuration files, you must assign the name of this queue to the new connector configuration standard property, ResponseQueue.